That is a picture of “Il Duomo di Milano”. Every big city in Italy has its Duomo. This cathedral is located in the main piazza in Milan, and is a beautiful sight. I have been to Milan about 3 times in the past year, and I have never seen Il Duomo not under renovation. The lower front, as you can see in the picture, is covered with scaffolding and billboard-type things. Oh, and it is definitely worth going into the Duomo (for free), it is a beautiful cathedral.
You can see the full size picture in our gallery.